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The Clinical Evaluation of a Food Additive: Assessment of Aspartame
 
 
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The Clinical Evaluation of a Food Additive: Assessment of Aspartame (Hardcover)

by Christian Tschanz (Author), Harriett H. Butchko (Author), W. Wayne Stargel (Author), Frank N. Kotsonis (Author) "Although the physician has for centuries been bound by the Hippocratic Oath, the charge in early times was to heal, regardless of the consequences of..." (more)
Key Phrases: mean plasma phenylalanine concentrations, plasma aspartate concentrations, erythrocyte amino acid levels, New York, Marcel Dekker, Concern Level (more...)
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Editorial Reviews
Product Description
This useful book reviews and analyzes the rigorous scientific, regulatory, and clinical testing and evaluation applied to the widely used food additive aspartame. In one compact volume you gain access to extensive information illustrating the increased recognition by regulatory agencies of the usefulness of human studies in evaluating new food additives. The Clinical Evaluation of a Food Additive: Assessment of Aspartame begins by describing the nuts and bolts of food additive safety evaluation in humans, including an insightful historical perspective of the development of good clinical practice guidelines. It provides the regulatory requirements for human research, as well as key elements for the design and conduct of human studies. The scientific and regulatory considerations of food additive safety are explored, including interesting descriptions of aspartame's key animal safety studies. In addition, the book reviews the medical postmarketing surveillance system developed for identifying and evaluating reports of aspartame's alleged adverse health effects. Through meticulous research and systematic clarity, The Clinical Evaluation of a Food Additive: Assessment of Aspartame provides work-saving, state-of-the-art examples to guide future testing and evaluation of tomorrow's food additives.

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Inside This Book (learn more)
First Sentence:
Although the physician has for centuries been bound by the Hippocratic Oath, the charge in early times was to heal, regardless of the consequences of the treatment or the wishes of the patient. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
mean plasma phenylalanine concentrations, plasma aspartate concentrations, erythrocyte amino acid levels, fasting plasma phenylalanine concentrations, aspartame dosing, aspartame loading, aspartame group, blood formate concentrations, adults administered aspartame, elevated plasma phenylalanine concentrations, adults heterozygous for phenylketonuria, normal postprandial range, aspartame fail, encephalopathic parameters, erythrocyte free amino acid levels, premarketing estimates, human tolerance studies, chronic aspartame ingestion, administered abuse doses, blood methanol concentrations, body weight aspartame, acute aspartame, lactating women administered aspartame, receiving aspartame, aspartame intake
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Marcel Dekker, Concern Level, Government Printing Office, Food Chem, World Health Organization, Raven Press, Department of Agriculture, Expert Committee, Oral Toxicity Study, Comments Toxicol, Department of Health, Inherited Metab, International Life Sciences Institute-Nutrition Foundation, Survey Methods, Boca Raton, Brain Res, Genetic Studies, Health Protection Branch, Hour Post-Dose, International Aspartame Workshop Proceedings, Space Environ, United States, Van Itallie, Child Psychol
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Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover | Surprise Me!
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